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pentobarbital will lessen the extent or outcome of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Sturdy or reasonable CYP3A4 inducers may well raise charge of diazepam elimination; consequently, efficacy of diazepam can be lessened.pentobarbital will lower the extent or effect of disopyramide by impact